Search

Language:中文ENGLISH

E-mail: sales_liu@bonabio.cn

Whatsapp: +86-18963064736

Wechat: +86-18963064736

QQ: 2862752579

TM: Bonabio

Address: Block D, Century Fortune Center, High-tech Zone, Jinan City, Shandong Province, China

Copyright(c)2020  ©  Shandong Bona Biological Technology Group Co., Ltd. 鲁ICP备12034225号-5

CONTACT US

PRODUCTS

ABOUT US

MESSAGES

TECHNOLOGY

TECHNOLOGY

BONA BIOTECHNOLOGY GROUP

Chromatography packing for extraction, separation and purification of ascomycin (ascomycin, immunomycin, FK520)

Classification:
Separation and purification process development
Author:
Source:
Release time:
2019/09/24 17:37
Page view
[Abstract]:
Ascomycin (ascomycin, immunomycin, FK520) is a twenty-three carbon macrolide compound, an ethyl analog of the immunosuppressant tacrolimus (FK-506), and a synthetic pimecrolimus (Trade name Elidel) precursor material.

Chromatography packing for extraction, separation and purification of ascomycin (ascomycin, immunomycin, FK520)

Ascomycin (ascomycin, immunomycin, FK520) is a twenty-three carbon macrolide compound, an ethyl analog of the immunosuppressant tacrolimus (FK-506), and a synthetic pimecrolimus (Trade name Elidel) precursor material. Since the launch of ascomycin and its derivatives, the market share has increased rapidly, and pimecrolimus has become the first clinical drug for transplant rejection after skin transplantation. Although great progress has been made in the fermentation and production of ascomycin, structural analogues appearing in the fermentation process have increased the difficulty of separation and purification of the substance.

Chromatography filler for separation and purification of ascomycin SKP-10-8300 SKL-30-4005