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Reverse chromatography medium for thymus method new separation and purification reverse chromatography packing reverse chromatography resin packing

Classification:
Separation and purification process development
Author:
Source:
Release time:
2019/09/24 17:34
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[Abstract]:
Thymosin α1 (Thymosin) is a 28 peptide with strong acidity, with a molecular weight of 3108 and an isoelectric point of 4.2. The N-terminal is acetylated. The synthesized crude peptide contains many impurities with molecular size and properties similar to the product, which is not easy to purify.

Thymosin α1 (Thymosin) is a 28 peptide with strong acidity, with a molecular weight of 3108 and an isoelectric point of 4.2. The N-terminal is acetylated. The synthesized crude peptide contains many impurities with molecular size and properties similar to the product, which is not easy to purify. After a long period of exploration and improvement, Jinan Bona Biotechnology Co., Ltd. has developed a medium for the separation and purification of thymosin α1, which can make the purity of thymosin α1 more than 99% without repeated reverse preparation. The production cost of the product is reduced, and the purity of the product is improved.

The specific process steps are as follows:

XD7HP resin adsorption analysis SKP-10-1300 reverse chromatography resin acetonitrile water chromatography

SKR-10-1200 C18 reversed silica gel, acetonitrile water reversed chromatography preparation

SKP-10-1300 resin deacidification and desalination freeze-drying

If you need to purchase the above chromatography media or request samples, please contact our company, our company will provide you with detailed technical support.

If you need to test the separation performance, our company also has a corresponding series of packed analysis columns.