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Vancomycin extraction, separation and purification process

Classification:
Separation and purification process development
Author:
Source:
Release time:
2019/09/24 17:26
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[Abstract]:
Vancomycin is a glycopeptide antibiotic isolated from the fermentation broth of a strain of Streptomycin orientalis by Micormick in 1956. It was approved by the US FDA in 1958 and was developed and marketed by Lilly.

Vancomycin is a glycopeptide antibiotic isolated from the fermentation broth of a strain of Streptomycin orientalis by Micormick in 1956. It was approved by the US FDA in 1958 and was developed and marketed by Lilly. It is used to treat infectious diseases caused by Gram-positive bacteria. Especially for the resistant Staphylococcus aureus and Clostridium difficile caused by lactam antibiotics. It was once hailed as the last line of defense against drug-resistant bacteria. Its unique antibacterial mechanism makes it widely used not only in clinical but also in animal husbandry.

With the application of new separation and extraction technology, the quality of vancomycin is continuously improved, and the toxic and side effects caused by low purity are gradually reduced. In order to further improve the quality, simplify the process, reduce labor intensity and production cost, Bona Bio has made a lot of improvements on the basis of the existing extraction process, and introduced advanced foreign technology to develop the SKP-10-4300 chromatography resin. The extraction and purification process is improved to stabilize the product purity above 95%, and the yield is 50%, and the production process is greatly simplified.

If you need to purchase SKP-10-4300 chromatography packing or request samples, please contact our company at 0531-88804339, our company will provide you with detailed technical support.